American Cruise Lines

America’s #1 River Cruise Line

American Cruise Lines carries passengers to the best of America aboard the newest fleet of riverboats and small ships in the United States. Traveling smooth inland waterways and magnificent rivers, destinations include the most historic, culturally unique and scenic areas in the U.S. All departure ports are conveniently located near major airports, creating an easy and relaxing travel experience. Now, with authentic paddlewheelers both in the Pacific Northwest on the Columbia and Snake Rivers and in the American Heartland on the Mississippi River, guests can experience the best of the American rivers in the elegance and comfort of the Queen of the West and the brand new Queen of the Mississippi, the first paddlewheeler of its kind to be built for the Mississippi River in nearly 20 years. Queen of the Mississippi offers a brand new way to experience the longest river system in North America by offering a never-before seen combination of 21st-century technology and first-class amenities, with the historic grandeur of classic American riverboats.

Ships

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Deals

  • Secrets The Vine Cancun (1)
    Packages
    Cancun, Mexico

    Elegant Escapes: Savor the Splendor of Secrets The Vine Cancun with Flights from Milwaukee!

    3-8 Nights + Nonstop Airfare from MKE

    Starting from $1,169

    per person

    3-8 Nights + Nonstop Airfare from MKE

    Starting from $1,169

    per person

  • Friends On The Beach 2
    Packages
    Cancun, Mexico

    Luxury Awaits in Cancun: Secrets The Vine + Direct Chicago O'Hare Flights!

    3-8 Nights + Nonstop Airfare from ORD

    Starting from $969

    per person

    3-8 Nights + Nonstop Airfare from ORD

    Starting from $969

    per person

  • Breathless Punta Cana Resort & Spa (13)
    Packages
    Dominican Republic, Caribbean

    Punta Cana Pulse: Experience the Excitement at Breathless Resort from Chicago!

    3-7 Nights + Nonstop Airfare from ORD

    Starting from $929

    per person

    3-7 Nights + Nonstop Airfare from ORD

    Starting from $929

    per person